Dr. Neesar Ahmed

School of Life Sciences

Designation	:	Associate Professor
Nature of Employment	:	Regular
Date of Joining	:	06/09/2013
Qualification	:	M.Sc. Ph.D
Phone	:	+91 9791024812
Email ID	:	[email protected]
Google Scholar link	:	https://scholar.google.com/citations?user=1cKYr1ZYh1YC&hl=en&oi=ao
Scopus Link	:	https://www.scopus.com/authid/detail.uri?authorId=55432664700
OrcidId	:	https://orcid.org/0000-0002-7367-2188

Educational Background

Ph.D (Biotechnology; Cancer Signaling) National Center for Cell Sciences (NCCS), Dept. of Biotechnology, Govt. of India, 2009, University of Pune, Pune, Maharashtra, India
M.Sc (Biotechnology) Aligarh Muslim University (AMU), Aligarh, Uttar Pradesh, India. 2004
B.Sc (Biochemistry) Aligarh Muslim University (AMU), Aligarh, Uttar Pradesh, India. 2002

Teaching and research Experience

Associate Professor, BSA Crescent Institute of Science and Technology, Chennai, Tamil Nadu, India, August 31, 2022 – till present
Assistant Professor (Selection Grade) , BSA Crescent Institute of Science and Technology, Chennai Tamil Nadu, India, Feb 2020—August 30, 2022
Assistant Professor, (Senior Grade) BSA Crescent Institute of Science and Technology, Chennai Tamil Nadu, India, Sep 2013-Feb 2020
Post Doc Fellow (Cancer Immunology), Karmanos Cancer Institute, Wayne State University, Detroit, Michigan, US, Jan 2011-Sep 2013
Senior Research Fellow, National Centre for Cell Sciences (NCCS), Dept. of Biotechnology, Govt. of India, Pune, Maharashtra, India, 2007-2010
Junior Research Fellow, National Centre for Cell Sciences (NCCS), Dept. of Biotechnology, Govt. of India, Pune, Maharashtra, India, 2005-2007

Honors and Awards

University Grant Commission- National Eligibility Test (UGC NET-JRF/SRF)
Qualified with fellowship in First Attempt-Joined National Center for Cell Sciences (NCCS), Dept of Biotechnology, Govt. of India, Pune for PhD.
Department of Biotechnology, Govt. of India-fellowship during Post Graduation-Two Years (M.Sc.)
GATE qualified in First attempt All India Rank-420

Research areas

Cancer Biology
Cancer Immunology
Inflammation biology
Tumor Microenvironment
Protein Chemistry
Lectins

Research outcomes

a. Research grants

Completed

PI Neesar Ahmed, DST-SERB Young Scientist Award (Rs. 25 Lakhs) 2014-2018 – completed

b. Publications

Number of Research Publications

International journals: 25
Invited talks delivered: 02

List of publications

AK Bommanaboina, S Jamal, N Ahmed.* Antitumor Activity of Taxol Engross Taxol-Caveolin-1 Interaction via Lipid Raft Structure—“Caveolae”. Applied Biochemistry and Biotechnology. 1-12, 2023 (Scopus Indexed) (Index factor 3.09). https://doi.org/10.1007/s12010-023-04355-7
M Basheeruddin, V Lavanya, N Ahmed, S Jamal*, Organic osmolyte betaine mitigates the deleterious effects of Diclofenac in vivo in wistar albino rats. Brazilian Journal of Pharmaceutical Sciences, 59, e201178, 2023, (Scopus Indexed) (Index factor 0.814). https:// doi: 10.3389/fmolb.2022.872905
J Kashifa Fathima, V Lavanya, S Jamal, N Ahmed*. The Effectiveness of Various Chemotherapeutic Agents in Cancer Treatment. Current Pharmacology Reports, 1-17, 2022 (Scopus Indexed) (Index factor 1.524). https://doi.org/10.1007/s40495-022-00289-6
M Gayathri, V Lavanya, S Jamal, N Ahmed*. Targeting Soluble Factors Involved in Inflammatory Cancer Microenvironment. Current Pharmacology Reports, 1-9, 2022, (Scopus Indexed) (Index factor 1.524). https://doi.org/10.1007/s40495-022-00291-y
Basheeruddin, S Khan, N Ahmed, S Jamal*.Effect of pH on Diclofenac–Lysozyme Interaction: Structural and Functional Aspect. Frontiers in Molecular Biosciences 9, 2022(Scopus Indexed) (Index factor 6.113). https:// doi:10.3389/fmolb.2022.872905
Logesh, V Lavanya, S Jamal, N Ahmed*. Designing of a Chimeric Vaccine Using EIS (Rv2416c) Protein Against Mycobacterium tuberculosis H37Rv: an Immunoinformatics Approach. Applied Biochemistry and Biotechnology 194 (1), 187-214, 2022 (Scopus Indexed) (Index factor 3.09). https://doi.org/10.1007/s12010-021-03760-0
Lavanya, AK Bommanabonia, N Ahmed, S Jamal*. Immunomodulatory Effects of Jacalin, a Dietary Plant Lectin on the Peripheral Blood Mononuclear Cells (PBMCs). Applied Biochemistry and Biotechnology, 194 (1), 587-599, 2022 (Scopus Indexed) (Index factor 3.09). https://doi.org/10.1007/s12010-021-03722-6
V Lavanya, S Jamal*, N Ahmed. Increased ERK phosphorylation and caveolin-1 expression on K562 human chronic myelogenous leukemia cells by jacalin, a dietary plant lectin. Glycoconjugate Journal 38 (3), 361-368, 2021 (Scopus Indexed) (Index factor 3.009). https://doi.org/10.1007/s10719-021-09998-4
M Chandhru, R Logesh, S Kutti Rani, N Ahmed, N Vasimalai .Green synthesis of silver nanoparticles from plant latex and their antibacterial and photocatalytic studies. Environmental Technology, 1-11, 2021 (Scopus Indexed) (Index factor 3.475). https:// doi: 10.1080/09593330.2021.1914181
Chandhru, R Logesh, SK Rani, N Ahmed, N Vasimalai. One-pot green route synthesis of silver nanoparticles from jack fruit seeds and their antibacterial activities with Escherichia coli and salmonella bacteria. Biocatalysis and Agricultural Biotechnology 20, 101241, 2019 (Scopus Indexed) (cite score 6.2). https://doi.org/10.1016/j.bcab.2019.101241
AA Adil, AK Bommanabonia, A Vaithy, S Kumar, M Waseem, S Jamal, N Ahmed. Differential expression of Helios, Neuropilin-1 and FoxP3 in head and neck squamous cell carcinoma (HNSCC) patients. 3 Biotech 9 (5), 1-10, 2019 (Scopus Indexed) (Index factor 2.893). https://doi.org/10.1007/s13205-019-1707-7
AAM Adil, L Vallinayagam, K Chitra, S Jamal, AK Pandurangan, N Ahmed. Increased Expression of TGF-β and IFN-γ in Peripheral Blood Mononuclear Cells (PBMCs) Cultured in Conditioned Medium (CM) of K562 Cell Culture. Journal of Environmental Pathology, Toxicology and Oncology 38 (2), 2019. (Scopus Indexed) (Index factor 3.567). https:// doi: 10.1615/JEnvironPatholToxicolOncol.2019029460
V Lavanya, BA Kumar, S Jamal, MKA Khan, N Ahmed*. Sub-Micellar Concentration of Sodium Dodecyl Sulphate Prevents Thermal Denaturation Induced Aggregation of Plant Lectin, Jacalin. The Protein journal 36 (1), 17-27, 2017 (Scopus Indexed) (Index factor 4.00). https:// DOI 10.1007/s10930-017-9694-1
V. Lavanya, Neesar Ahmed, Md Khurshid A. Khan & Shazia Jamal*. Sustained Mitogenic Effect on K562 Human Chronic Myelogenous Leukemia Cells by Dietary Lectin, Jacalin. Glycoconjugate Journal (2016), Volume 33, Issue 6, pp 877-886. (Scopus Indexed) (Index factor 3.009). https:// DOI 10.1007/s10719-016-9725-8
Adil, V Lavanya, S Jamal, N Ahmed*. Cancer immunotherapy: Targeting immunosuppressive tumor microenvironment. Oncobiology and Targets 1 (1), 16-16, 2014.
V Lavanya, AM Adil, N Ahmed, S Jamal*. Lectins-the promising cancer therapeutics. Oncobiology and Targets 1 (1), 12-12 (2014).
V Lavanya, AM Adil, N Ahmed, S Jamal*. Small molecule inhibitors as emerging cancer therapeutics. Integr Cancer Sci Ther 1 (3), 39-46 (2014). https:// doi: 10.15761/ICST.1000109

Book Chapters

The Multifaceted Role of Natural Agents in Colitis-Associated Cancer Prevention and Therapy. AKK Pandurangan, SK Anandasadagopan, N Ahmed. Diagnostic and Treatment Methods for Ulcerative Colitis and Colitis (2021).
Protagonist of Immuno-Profiling, Immuno-Scoring, and Immunotherapy Towards Colitis-Associated Cancer: Systematic Review M Adil, AK Pandurangan, M Waseem, N Ahmed
Diagnostic and Treatment Methods for Ulcerative Colitis and Colitis. (2021).
Ubiquitin Mediated Posttranslational Modification of Proteins Involved in Various Signaling Diseases. V Lavanya, S Jamal, N Ahmed
Protein Modificomics, 109-130 (2019).

c. Research guidance

Ph.D

Graduated: 01, Ongoing: 02

List of Scholars completed

S.No	Name of the scholar	Title of the thesis	Year of registration	year of Completion	Scholarship details	Outcomes
1.	Dr. Adil Mohammed A A	Immunosuppresive cell within Tumor microenvironment	2014	2019	Maulana Azad National fellowship – UGC, India (2014-2019)	Publications:10 Conference presentations: 12

List of Scholars ongoing

S.No	Name of the scholar	Title of the thesis	Year of registration	Year of Completion	Scholarship details	Outcomes
1.	Anil B Kumar	Ubiquitin mediated regulation of the Inflammatory Tumor Microenviromnment in specialized lipid raft	2015	–	ICMR SRF	Publications:06, Conference presentations: 12
2.	Logesh R	Immunology of Mtb within macrophage	2016	–	ICMR SRF	Publications: 03, Conference presentations: 8

M.Sc/M.Tech

Completed projects: 27
Ongoing projects: 02

S.No	Name of the student	Title of the project	Year of award	Outcomes
1	Anil K B	Immunomodulatory effect of jacalin purified from jack fruit seed	2015 June	Conference presentations:2
2	B. Famidha	Anti-inflammatory drug diclofenac induced structural and conformational change in Bovine serum albumin	2016 May	Conference presentations:2
3	Logesh	Immunomodulatory effect of LPS purified from diverse gram negative bacteria	2016 May	Conference presentations:2
4	Sakaram	“IMMUNOMODULATORY EFFECTS OF DIETARY LECTIN ‘JACALIN’ FROM JACKFRUIT (ARTOCARPUS INTEGRIFOLIA) SEEDS, ON HUMAN PERIPHERAL BLOOD MONONUCLEAR CELLS (PBMCS)”	2017 May	Conference presentations:2
5	Balaji Prasanna Kumar G	Increased expression of IL-2 and TGF beta in Jacalin stimulated human PBMCs and its effects on ME 180 cancer cells proliferation	2019 May	Conference presentations:2
6	S. Pavithra	Effcect of recombinant EIS protein in Mtb on bacterial culture and PBMCs proliferation	2019 May	Conference presentations:2
7	TS Priyadharshini	An overview of enhanced intracellular survival protein in mycobacterium tubercluosis	2020 May	Conference presentations:2
8	Dasarimanoj	In Silico characterization of Rv1477 gene product from mycobacterium tubercluosis	2020 May	Conference presentations:2
9	G Roni Mrudula	In Silico characterization of Rv0169 gene product from mycobacterium tubercluosis	2020 May	Conference presentations:2
10	J. Jerrina Marial	A Study on the effects of osmolytes on protein stability	2021 July	Conference presentations:2
11	Noornisha	Nanoparticle-based formulation, evaluation, and development of Facewash	2021 July	Conference presentations:2
12	S.Keerthana	Role of Caveolae in cell signaling	2021 July	Conference presentations:2
13	V.Krithika	Effect of temperature on the thermal denaturation of lectin crude lysate from green pea	2021 July	Conference presentations:2
14	Tesy Ranjana A	Insilico analysis of EIS (Enhanced Intracellular Survival Protein ) of Mycobacterium tuberculosis	2021 July	Conference presentations:2
15	Monica	Reveiw on Antibacterial activity of Vitex negundo against noscomial pathogens	2021 July	Conference presentations:2
16	D. Sudha	To study the stability and specificity of Jacalin: A dietary plant lectin	2021 July	Conference presentations:2
17	Aberna S	Combinatorial Chemotherapy of Taxol with methanolic extract of Allium cepa targeting breast cancer cell lines (MCF-7)	2022 May	Conference presentations:2
18	A.S. Faiza Fathima	Combinatorial Chemotherapy of Taxol with methanolic extract of Blue Beri targeting breast cancer cell lines (MCF-7)	2022 May	Conference presentations:2
19	Anitha M	Immunommodulatory and inhibitory effect of recombinant EIS protein from Mtb H37Rv	2023 May	Conference presentations:2
20	Yasmin Banu C	Extraction and characterization of active components of Ajwa Date Extract and its biological activities.	2023 May	Conference presentations:2
21	Vaishnavi S	Extraction and characterization of active components of Apple Extract and its biological activities.	2023 May	Conference presentations:2
22	S Keerthana	Effect of osmolytes glycine on jacalin-a plant lectin	2023 May	Conference presentations:2
23	K Asma	Effect of glycerol on the stability of jacalin(a plant lectin)	2023 May	Conference presentations:2
24	Pavithra A	Effect of Jacalin on Invitro tumor microenvironmentTME crosstalk between cancder and Immune Cells	2023 May	Conference presentations:2
25	Jhawahar M R	Characterization and Biological applications of Plectranthusamboinicus Leaf Extract	2023 May	Publications:- Conference presentations:2
26	Lucky Charan S	Biosynthesis of Iron oxide nanoparticles using Pisum sativum lectin extract and its biological application	2023 May	Conference presentations:2
27	Naveena R	Characterizing the physical and biological properties of lectins in Pisum sativum lysate	2023 May	Conference presentations:2

B.Tech

Completed projects: 30
Ongoing projects :05

S.No	Name of the student	Title of the project	Year of award	Outcomes
1	Yogeswari	Effect of Recombinant EIS (Rv 2416) protein of Mtb on Human PBMCs	2018 June	Conference presentations: 2
2	R Abirami	Analysis of Markers og Tregs on Human head & Neck squamous cell carcinoma	2018 June	Conference presentations: 2
3	ShadmaniAhrar	Purification and characterization of EIS protein involved in survival of Mtb in Macrophage	2018 June	Conference presentations: 2
4	Abeer	Role of Treg Cells and Association of FOXP3 and GATA 3 in TME	2018 June	Conference presentations: 2
5	Aamina Afshan	Cloning and expression of RpfB gene in Mtb	2018 June	Conference presentations: 2
6	Arvind Kumar Sharma	Insilico structural and functional characterization of Mtb gene RV1085c of H35Rv Strain	2019 May	Conference presentations: 2
7	Mohamed Adhnan P	Evaluation of AnticancerousProperity of SG extract & analysis of antagonist properties of small coumpound of SG Extract Against TLR4	2019 May	Conference presentations: 2
8	Fathima H B	Glycine Inhibits Thermal Aggregation in rEIS protein	2019 May	Conference presentations: 2
9	N Balamurugan	To study the chemotheraphy induced adverse drug reaction in metastatic breast cancer	2019 May	Conference presentations: 2
10	Nada Rafat	Effect of soluble factors from cancer cell CM on PBMCs	2019 May	Conference presentations: 2
11	Mohseen Fathima S	Immunomolecular markers in Breast Cancer and Exploration of their role in Laboratory diagnosis	2020 July	Publications: -Conference presentations: 2
12	M Gayathri	TARGETING SOLUBLE FACTORS INVOLVED IN INFLAMMATORY CANCER MICROENVIRONMENT	2020 July	Conference presentations: 2
13	Kashifa Fathima J	COMBINATION OF NATURAL PRODUCTS WITH CHEMOTHERAPY AGAINST CANCER	2020 July	Conference presentations: 2
14	S Anuradha	Lectin Based Nanoparticles synthesis and its biological Applications	2020 July	Conference presentations: 2
15	Pradeepa A	isolation, Purification and functional analysis of Lectin from Kidney bean	2020 July	Conference presentations: 2
16	Abdullah Naveed Khan A	Ins Silico Characterization and structural prediction on Rv1884C (rpfC) gene product of Mycobacterium tuberculosis	2021 July	Conference presentations: 2
17	Aditya Subramanian V	In Silico design of multiepitope vaccine candidate against membrane protein (M Protein) of SARs CoV-2: An Immunoinformatic approach	2021 July	Conference presentations: 2
18	Harini R M	Topical pain relief medication using leaf of Morinda tinctoria and Eucalyptus globulus combination for arthritis patients-A review	2021 July	Conference presentations: 2
19	Nashiha Begum K	Effect of sulforaphane in variuos human diseases-A review	2021 July	Conference presentations: 2
20	Sadiya S	Effect of junk Food on human health	2021 July	Conference presentations: 2
21	Shobana. V.S	Molecular docking of Astaxanthin with incoprotein	2021 July	Conference presentations: 2
22	Supraja Tap	Green Synthesis of Zinc oxide nanoparticles using Solanum lycopersicum extract for breast cancer treatment: Insilico and in-vitro analysis	2021 July	Conference presentations: 2
23	Karishma. G.R	Anti-hepatotoxic effect of phytochemicals isolated from red lentil seeds (Lens culinaris) against HMGB1 protein: an insilico approach	2021 July	Conference presentations: 2
24	Mohammed Abdul Ahad. R	Properities and sourses of pectin to explore its Potential as an efficient food pacakging materials- A review	2021 July	Conference presentations: 2
25	Mumtaz Jabeen.A	Bebeficial aspects of indian spices	2021 July	Conference presentations: 2
26	Manu Sam	Extraction and study of the flavonoid quercetin from seeds and leaves of Trigonella foenum graecum	2022 June	Conference presentations: 2
27	Vaishnavi. S	Green synthesis, Characterization,Cytotoxicity and Anti inflammatory activity of Iron oxide nanoparticles	2022 June	Conference presentations: 2
28	Fathima Shifana SA	Decellularized based hydrogel from untanned leather wastes	2023 May	Conference presentations: 2
29	Gayathri R	Invitro Investigation of Anti-inflammatory, antioxidant activity and evalution of the phytochemical profile of Arthocarpushetrophyllus	2023 May	Conference presentations: 2
30	Falak Zohra	Effect of osmolytes on stability of recombinant EIS from Mtb H37v	2023 May	Conference presentations: 2

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School of Life Sciences

Dr. Neesar Ahmed